John R Perfect Selected Research

Cryptococcosis

7/2018	Present and Future Therapy of Cryptococcus Infections.
1/2017	Disseminated Cryptococcosis With Brain Involvement in Patients With Chronic Lymphoid Malignancies on Ibrutinib.
1/2016	Isavuconazole Treatment of Cryptococcosis and Dimorphic Mycoses.
2/2014	Impact of surfactant protein D, interleukin-5, and eosinophilia on Cryptococcosis.
6/2013	Approaches to antifungal therapies and their effectiveness among patients with cryptococcosis.
4/2013	Fungal diagnosis: how do we do it and can we do better?
7/2012	Surfactant protein D facilitates Cryptococcus neoformans infection.
6/2012	A chronological history of the International Conference on Cryptococcus and Cryptococcosis (ICCC), an invaluable forum for growth of the cryptococcal research field and clinical practice.
1/2011	Cryptococcus neoformans requires a functional glycolytic pathway for disease but not persistence in the host.
10/2010	Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis.

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John R Perfect Research Topics

Disease

62	Infections 04/2022 - 03/2002
38	Mycoses (Diseases, Fungus) 06/2022 - 01/2002
34	Invasive Fungal Infections 03/2020 - 03/2002
18	Aspergillosis 03/2020 - 03/2002
16	Cryptococcosis 07/2018 - 05/2003
13	Invasive Candidiasis 08/2022 - 05/2003
11	Neoplasms (Cancer) 03/2020 - 10/2002
10	Cryptococcal Meningitis 12/2019 - 01/2013
9	Meningoencephalitis 12/2021 - 02/2010
8	Candidiasis (Moniliasis) 08/2022 - 05/2003
8	Candidemia 01/2019 - 07/2003
7	Neutropenia 06/2014 - 11/2004
5	Mucormycosis 01/2022 - 03/2012
4	Systemic candidiasis 01/2016 - 08/2010
4	Hematologic Neoplasms (Hematological Malignancy) 04/2015 - 01/2007
4	Fever (Fevers) 01/2012 - 05/2003
3	Pneumonia (Pneumonitis) 12/2021 - 04/2002
3	Inflammation (Inflammations) 10/2018 - 01/2013
3	Fusariosis 11/2016 - 05/2003
3	Sepsis (Septicemia) 08/2011 - 09/2005
3	Zygomycosis (Phycomycosis) 12/2009 - 11/2004
3	Critical Illness (Critically Ill) 07/2009 - 03/2009
2	Meningitis 04/2021 - 10/2002
2	Aneuploidy (Aneuploid) 12/2019 - 11/2011
2	Acquired Immunodeficiency Syndrome (AIDS) 01/2017 - 02/2014
2	Central Nervous System Infections (Central Nervous System Infection) 11/2013 - 01/2013
2	Fungemia 02/2012 - 09/2005
2	Disease Progression 10/2011 - 01/2002
2	Fungal Lung Diseases 01/2011 - 01/2004
2	Drug-Related Side Effects and Adverse Reactions 12/2009 - 05/2008
2	Immune Reconstitution Inflammatory Syndrome 05/2008 - 06/2007
2	Communicable Diseases (Infectious Diseases) 12/2004 - 02/2003
2	Osteomyelitis 03/2004 - 08/2003
2	scedosporiosis 05/2003 - 03/2002
1	Coinfection 01/2022
1	Coccidioidomycosis 12/2021
1	Central Nervous System Diseases (CNS Diseases) 10/2021
1	Craniocerebral Trauma (Head Injury) 04/2021
1	Wounds and Injuries (Trauma) 04/2021

Drug/Important Bio-Agent (IBA)

18	Pharmaceutical PreparationsIBA 01/2017 - 02/2003
17	Antifungal AgentsIBA 06/2022 - 05/2003
15	Amphotericin B (Amphotericin)FDA LinkGeneric 02/2022 - 04/2002
15	Fluconazole (Zonal)FDA LinkGeneric 12/2021 - 11/2004
15	Voriconazole (Vfend)FDA LinkGeneric 01/2019 - 03/2002
9	CytokinesIBA 01/2019 - 02/2005
9	liposomal amphotericin B FDA Link 01/2017 - 03/2004
9	posaconazole FDA Link 06/2014 - 03/2004
7	EchinocandinsIBA 09/2017 - 04/2002
7	Caspofungin (Cancidas)FDA Link 11/2006 - 04/2002
6	isavuconazoleIBA 01/2019 - 01/2016
5	TriazolesIBA 01/2019 - 04/2002
4	Biomarkers (Surrogate Marker)IBA 06/2022 - 02/2011
4	Flucytosine (Ancobon)FDA Link 10/2021 - 02/2010
4	AzolesIBA 01/2021 - 12/2004
4	AntigensIBA 11/2016 - 01/2011
4	CalcineurinIBA 10/2007 - 06/2003
3	Complement System Proteins (Complement)IBA 04/2022 - 10/2012
3	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022 - 09/2006
3	galactomannanIBA 11/2016 - 07/2007
3	Itraconazole (Sporanox)FDA LinkGeneric 06/2014 - 05/2003
3	deoxycholate drug combination amphotericin BIBA 01/2014 - 11/2004
3	polihexanideIBA 09/2011 - 08/2003
3	EnzymesIBA 05/2003 - 10/2002
2	AerosolsIBA 02/2022 - 01/2004
2	Inositol (Myoinositol)IBA 12/2021 - 01/2013
2	ibrutinibIBA 03/2020 - 01/2017
2	LipidsIBA 01/2019 - 02/2010
2	Capsules (Microcapsules)IBA 10/2018 - 01/2018
2	ProdrugsIBA 01/2018 - 07/2016
2	TrehaloseIBA 01/2017 - 10/2006
2	DNA (Deoxyribonucleic Acid)IBA 11/2016 - 08/2011
2	Pulmonary Surfactant-Associated Protein D (Surfactant Protein D)IBA 02/2014 - 07/2012
2	GlucansIBA 04/2013 - 10/2011
2	Deferasirox FDA Link 08/2012 - 03/2012
2	Anidulafungin FDA Link 01/2012 - 05/2006
2	polyglucosanIBA 01/2012 - 11/2010
2	dectin 1IBA 10/2011 - 10/2009
2	Cyclosporine (Ciclosporin)FDA LinkGeneric 09/2011 - 10/2007
2	Glucose (Dextrose)FDA LinkGeneric 01/2011 - 08/2004
2	Ergosterol (Lumisterol)IBA 08/2010 - 10/2007
2	Micafungin (FK463)FDA Link 07/2010 - 05/2006
2	VaccinesIBA 03/2007 - 02/2005
1	ibrexafungerpIBA 08/2022
1	Investigational DrugsIBA 08/2022
1	salicylhydroxamic acid (SHAM)IBA 04/2022
1	Dosage Forms (Dosage Form)IBA 02/2022
1	Antiviral Agents (Antivirals)IBA 01/2022

Therapy/Procedure

62	Therapeutics 12/2021 - 01/2002
6	Drug Therapy (Chemotherapy) 09/2006 - 04/2002
4	Lung Transplantation 09/2020 - 01/2002
4	Salvage Therapy 09/2008 - 05/2003
3	Bone Marrow Transplantation (Transplantation, Bone Marrow) 07/2007 - 10/2002
2	Catheters 01/2021 - 01/2018
2	Debridement 01/2017 - 08/2003
2	Central Venous Catheters 08/2011 - 11/2003
2	Organ Transplantation 01/2011 - 09/2006
2	Hematopoietic Stem Cell Transplantation 06/2009 - 01/2007
2	Transplantation 07/2003 - 01/2002
1	Injections 02/2022
1	Length of Stay 04/2021